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Same rule as any safari: neutral khaki, tan, beige, and muted green blend into the bush and hide dust well. Avoid blue and black specifically — both colors are known to attract tsetse flies, present in parts of northern Botswana including areas around the Delta and Chobe. Bright white stands out badly on game drives, fine only for evenings back at the lodge.
Closed-toe shoes matter more here than on a typical game-drive-only safari, specifically because of mokoro trips: you're stepping in and out of a low, narrow canoe at the water's edge, often on uneven or muddy ground.
Malaria risk runs across the whole country, not just specific regions — repellent matters throughout, not only in the Delta.
Mokoro canoes sit low in the water, and splashes happen — worth protecting anything you're not willing to risk.
Malaria prophylaxis is a separate, prescription-only decision — talk to a doctor or travel clinic before you go rather than relying on repellent alone.